Can I Get Disability Benefits for Treatment-Resistant Depression in 2025?

Anthony Tanoos • July 27, 2025

What is Treatment-Resistant Depression?

A woman is covering her ears with her hands in a dark room.

Treatment-resistant depression (TRD) is a serious mental health condition where individuals do not respond to at least two different antidepressant treatments. As awareness and diagnoses increase, more people are asking: Can I get disability for treatment-resistant depression in 2025?


The answer is yes—if your symptoms prevent you from working full-time and meet the criteria laid out by the Social Security Administration (SSA).


Why is This a Growing Disability Claim?

In the wake of the pandemic and economic stressors, mental health conditions—especially chronic ones like TRD—are now being viewed differently by SSA judges. But claims still require detailed documentation and a strategic approach.


How the SSA Evaluates Depression Claims

The SSA reviews claims under Listing 12.04 for Depressive, Bipolar, and Related Disorders. To qualify, you’ll need:

  • Medical evidence from a licensed psychiatrist or psychologist.
  • A record of medications tried and failed.
  • Proof that depression impairs concentration, ability to work with others, or manage oneself.
  • Evidence of repeated hospitalizations, therapy, or failed medication regimens.


For TRD specifically, showing that you’ve exhausted multiple treatment avenues is key.


Tips to Strengthen Your TRD Disability Claim

  • Keep a daily symptom journal. This supports the “longitudinal” evidence SSA requires.
  • Get a Residual Functional Capacity (RFC) assessment from your doctor that shows you cannot sustain full-time work.
  • Avoid gaps in treatment. SSA may deny claims if you’re not consistently seeking help.


Final Thoughts

TRD is a real, disabling condition. With the right approach and documentation, you can qualify for SSDI or SSI. If you’ve been denied before or are unsure where to start, let our experienced team handle your case—with modern tools and compassionate help.

Hourglass with red sand, symbolizing the passage of time.
By Anthony Tanoos September 10, 2025
Wondering how long it takes to get SSD back pay in 2025? Learn the timelines for SSI and SSDI, how delays happen, and estimate your benefits instantly.
Woman in a yellow hard hat, safety glasses, and gloves working on an engine in a cluttered workshop.
By Anthony Tanoos September 8, 2025
Learn the 2025 SGA limits for Social Security Disability, how work earnings affect your claim, and how Crossroads Disability can help you qualify.
Person holding a fan of assorted US dollar bills, including $20 and $50 denominations.
By Anthony Tanoos September 4, 2025
Learn how Social Security Disability back pay works in 2025, how it grows at each stage, and estimate your benefits with our free back pay calculator.
Person resting on floor, head on arms; contemplative expression, neutral-toned room and rug.
By Anthony Tanoos September 2, 2025
Most SSD claims are denied in 2025. Learn the top reasons for denial and how Crossroads Disability can help you avoid mistakes and win your case.
Person using a calculator on architectural blueprints, calculating numbers, close up.
By Anthony Tanoos August 29, 2025
Use our free Disability Benefits Calculator to see your potential monthly SSD payments, back pay, and Medicare/Medicaid eligibility in 2025.
Gavel on a wooden table; a person in a suit works on a laptop, near documents.
By Anthony Tanoos August 27, 2025
Wondering if you can win SSD benefits without a lawyer in 2025? Learn why legal help matters and try our free disability calculator & case evaluation.
Woman in wheelchair working on laptop at a wooden table, brick wall background.
By Anthony Tanoos August 25, 2025
Need Social Security Disability help in Terre Haute, Indiana? Learn how to apply, appeal, and win your SSD case with Crossroads Disability. Free evaluation.
Man in suit leans on desk in a wood-paneled office with a US flag; looks stern.
By Anthony Tanoos August 23, 2025
Denied Social Security Disability in 2025? Learn why appeals are where most people win — and how Crossroads Disability Law can fight for your benefits.
Rolled-up US dollar bills of varying denominations, scattered on a white surface.
By Anthony Tanoos August 21, 2025
Learn how Social Security Disability back pay works, how far back it goes, when you’ll get paid, and how a lawyer can help maximize your benefits.
Close-up black and white of an elderly woman's face, focusing on her eyes and wrinkles, showing signs of aging.
By Anthony Tanoos August 18, 2025
Learn how age 60 improves your chances of getting Social Security Disability. Find out why filing now can protect your retirement benefits.
Show More