Can I Get Disability Benefits for Treatment-Resistant Depression in 2025?

Anthony Tanoos • July 27, 2025

What is Treatment-Resistant Depression?

A woman is covering her ears with her hands in a dark room.

Treatment-resistant depression (TRD) is a serious mental health condition where individuals do not respond to at least two different antidepressant treatments. As awareness and diagnoses increase, more people are asking: Can I get disability for treatment-resistant depression in 2025?


The answer is yes—if your symptoms prevent you from working full-time and meet the criteria laid out by the Social Security Administration (SSA).


Why is This a Growing Disability Claim?

In the wake of the pandemic and economic stressors, mental health conditions—especially chronic ones like TRD—are now being viewed differently by SSA judges. But claims still require detailed documentation and a strategic approach.


How the SSA Evaluates Depression Claims

The SSA reviews claims under Listing 12.04 for Depressive, Bipolar, and Related Disorders. To qualify, you’ll need:

  • Medical evidence from a licensed psychiatrist or psychologist.
  • A record of medications tried and failed.
  • Proof that depression impairs concentration, ability to work with others, or manage oneself.
  • Evidence of repeated hospitalizations, therapy, or failed medication regimens.


For TRD specifically, showing that you’ve exhausted multiple treatment avenues is key.


Tips to Strengthen Your TRD Disability Claim

  • Keep a daily symptom journal. This supports the “longitudinal” evidence SSA requires.
  • Get a Residual Functional Capacity (RFC) assessment from your doctor that shows you cannot sustain full-time work.
  • Avoid gaps in treatment. SSA may deny claims if you’re not consistently seeking help.


Final Thoughts

TRD is a real, disabling condition. With the right approach and documentation, you can qualify for SSDI or SSI. If you’ve been denied before or are unsure where to start, let our experienced team handle your case—with modern tools and compassionate help.

Hand writing
By Anthony Tanoos February 18, 2026
Learn how Step 1 of the Social Security Disability process works, what Substantial Gainful Activity (SGA) means, and how working can impact your claim.
Person sitting, clutching stomach, possibly in pain. Beige pants, blue sweater, neutral setting.
By Anthony Tanoos February 12, 2026
Learn what a medically determinable impairment is, why Social Security requires objective medical evidence, and how proper documentation affects disability claims.
Person writing on a document labeled
By Anthony Tanoos February 4, 2026
Denied Social Security Disability? Learn why appealing initial and reconsideration denials matters, how hearings work, and how proper preparation can improve your chances.
Person in a white t-shirt stands in a shower, head down, arms raised against the tiled wall.
By Anthony Tanoos January 29, 2026
Learn the truth about how hard it is to get Social Security Disability benefits, why so many claims are denied, and how legal guidance can help. No fee unless we win
Red check mark inside a black square on a white checklist.
By Anthony Tanoos January 21, 2026
Explore Social Security Disability approval rates across initial, reconsideration, and hearing levels — including how different hearing offices vary and effects.
Woman with hand on forehead, looking stressed at paperwork on a desk.
By Anthony Tanoos January 12, 2026
Learn what the Social Security Work History Report is, why it’s critical to your disability claim, and how mistakes on this form can lead to denial.
Man with bare torso, in grey pants, arches back and touches his back with both hands.
By Anthony Tanoos January 7, 2026
Learn what counts as a “severe impairment” in Social Security Disability claims, how severity is defined, and why proving at least one severe condition is essential.
A person kneeling, using a grinder, sparks flying.
By Anthony Tanoos January 2, 2026
Learn how Step 4 of the Social Security Disability process works, how SSA evaluates your past relevant work, and why your RFC and work history are so important.
Person using walker assisted by another exiting a car.
By Anthony Tanoos December 19, 2025
Learn how a medically necessary walker can significantly increase your chances of winning Social Security Disability benefits and why SSA gives it strong weight.
Person signing a document at a white table, others' hands visible. Pink shirt, blue pen, papers.
By Anthony Tanoos December 15, 2025
Learn what a protective filing date is, how it affects back pay and benefit start dates, and why preserving it is critical in SSDI and SSI claims.
Show More